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PARMISOLE ADE+B®
Reg. SAGARPA: Q-0021-045
ANTIHELMÍNTIC
VETERINARY USE
INJECTABLE SULUTION. WIDE SPECTRUM POLIVITAMINIC ANTIHELMINTIC
FORMULA:
| Each 100 ml contains: |
|
| Levamisol HCl |
12 g |
| Vitamin-A |
10,000,000 U.I. |
| Vitamin-D2 |
1,500,000 U.I. |
| Vitamin-E |
1,000 U.I. |
| Vitamin-B1 |
800 mg |
| Vitamin-B2 |
300 mg |
| Vitamin-B6 |
400 mg |
| Vehicle c.b.p. |
100 ml |
INDICATIONS:
At administration in cattle, swine, sheep and goats it is efficient for therapy of gastrointestinal and pulmonary parasite infestations. Because of it is formulation it counteracts vitamin deficiency because of poor feed quality in long dry seasons.
It formulation confers antiemetic, antineuritic and haematopoietic actions avoiding problems like rachitic disease, growth, reproductive and milk production decline.
DOSE:
Gastrointestinal parasites: 1 ml for each 20 kg body weight.
Pulmonary parasite: 1 ml for each 16 kg body weight.
Note: Do not administer more than 15 ml per site.
ROUTE OF ADMINISTRACTION: Intramuscular deep.
WARNINGS:
Cattle: Do not use this product 72 hours before slaughter of animals intended for human consumption.
Do not use for human consumption milk from animals treated with this product until 3 days after last dose.
Swine, Sheep and Goats: Do not use this product 72 hours before slaughter of animals intended for human consumption.
Keep in a dark and fresh place for storing.
PRESENTATION: 20, 100 and 500 ml vials
CONSULT VETERINARIAN
MEDICAL PRESCRIPTION IS NECESSARY FOR SALE
PARMISOLE ADE+B® contains all vitamins needed by domestic animals.
VITAMIN A. There are atl least 12 derivates in nature. It is essential for glycoprotein synthesis: cell proliferation, vision (rodopcine formation), bone remodelation, functional reproduction of the skin. It is foun in green forages, but it degrades fast. It is the most deficient acquired in horses with usual diets. Colostrums is rich in Vitamin A. deficiencies are causes by: In growth: poor quality forage, stored for a long time or just with oats or barley. It may have variable grades of night blindness, anorexia, weakness, wire hair, convulsions (in extremes), tearing, respiratory infections, salival abscesses, foot dryness, sking hyperkeratinized, drop in conception rate, intracraneal pressure elevation, fetus development problems, failures in immune response, spermatogenesis problems.
Vitamin A deficiencies in cattle are related with a bad general body condition and with problems in production, wire hair and disease tendency. Suplement of PARMISOLE ADE+B® avoids these problems or corrects them if already present.
VITAMIN D. Involved with calcium and PTH in bone maintenance and growth, vitamins D2 and D3 ⇒ 1,25 dihydricolecalcipherol, dehydroxicolecalcipherol, are found in liver and kidney respectively. A deficiency in vitamin D from a nutritional problem or a deficient sunlight exposure, may cause rachitic young animals and osteomalasya in adults and that is the reason for its supplement either alone or with other vitamin elements. Vitamins are necessary even in well fed animals. It supplement rises reserves of these vitamins and, particularly in horses with susceptibility or genetic predisposition for one disease. For instance, it is known that absorption of these vitamins together with some of B complex are seriously compromised after entero-abdominal surgery, diarrhea, etc. therefore it is recommended to use vitamin B complex vitamins, liposoluble in low doses but repeatedly and vitamin C. even if ostechondrosis is multifactorial, its has been related to an excess in calcium en diet combined with an excess of vitamin D.
VITAMIN E. Antioxidant that prevents peroxidation of membrane lipids leads to tissue preservation, specially with exercise and also reduces free O2 radicals. Tocopherols are more active (being alfa the most potent) and is found in alfalfa, grains, cereals. They are essential to immune system work.
VITAMIN B-1. (Tiamin) Is a pyrimidin molecule united by a tyazol bond with metylen, and is a hydrosoluble vitamin. Its activity consists is to functions as a co-enzyme in essential molecule formation in Krebs cycle and fatty acid synthesis. Specially nervous tissue is susceptible to disorders in case of deficiency. It is well absorbed in gastrointestinal tract by passive diffusion and active transport.
VITAMIN B-2. (Riboflavin) is a molecule with a ribose chain, and belongs to hydrosoluble vitamins group. It has an important role in carbohydrate metabolism, aminoacids and lipids, mitocondrial respiration and oxidative phosphorilation.
VITAMIN B-6. The three forms (pyridoxin, pryridoxal and pyridoxamine), are pyridin substituted compounds,. and belongs to hydrosoluble vitamins group. It acts in a wide range of reactions in metabolism and aminoacid conversions. It is absorbed mainly in small intestine by passive diffusion and is transported to liver where it is metabolized and exported.
VITAMIN B-12. (cyanocobalamine) it is a corrinoid molecule (four pyrrol nucleus coordinated by a central cobaltum molecule), and belongs to hydrosoluble vitamins group. It is involved in coline and metionin synthesis, and is very important in nuclear maduration and cell division. Particularly in erytrhopoiesis it is absorbed in small intestine by a transporter method.
NICOTINAMIDE. It is an amid on nyacine (vitamin B-3), and belongs to hydrosoluble vitamins group.. it works in oxidateive-reductive reactions and metabolic processes of carbohydrates, lipogenesis, oxidation and fatty acid synthesis, degradation and synthesis of aminoacids and steroid synthesis. It is absorbed in gastrointestinal tract by passive diffusion.
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