|
MASTOSEC T®
Reg. SAGARPA:Q-0021-089
INTRAMAMARY ANTIMICROOBIAL
VETERINARY USE
INTRAMMAMARY SOLUTION. LONG TIME INTRAMMARY THERAPY FOR COWS IN DRY PERIOD
FORMULA:
Each syringe contains in suspension: |
|
Cloxacillin benzatinic equivalent to
of cloxacillin base |
0.500 g de cloxacilina base |
Dihydrostreptomycin sulphate equivalent to
dihydrostreptomycin base |
0.500 g dihidroestreptomicina base |
| Penicillina G benzatine |
500,000 U.I. |
| Flumetasone pivalate |
0.250 mg |
| Papain |
0.250 g |
| Vehicle q.s. |
9 ml |
INDICATIONS:
Therapy and prevention of mammary gland infections occurring during cow’s dry period.
DOSE
One syringe per quarter at the end of productive period (previous to feed change and after some days of the new regime empty for the last time).
ROUTE OF ADMINISTRATION: Intrammamary
It is recommended after milking, after udder cleaning and disinfection with an antiseptic, the total content of syringe must be administered en each nipple. After removing syringe, a rotary massage should be done and ascending to the udder with both hands, for a better antibiotic distribution in each quarter and at the end a sealing liquid must be put at each nipple.
WARNINGS:
Because of the long action of this product, it should not be used in lactating cows.
Treated animals should not be slaughtered for human consumption until 60 days after last dose.
It is indicated only for cow drying, once lactation has started do not consume milk durig first 48 hours after labor.
- Shake before use.
- Keep in a dark and fresh place for storing.
PRESENTATION: Box with 20 syringes
CONSULT VETERINARIAN
MEDICAL PRESCRIPTION IS NECESSARY FOR SALE
Formulation of MASTOSEC-T® contains the best antimicrobials for controlling Gram-positive bacteria growth, which are the main mammary gland colonizers during dry period. It is known that the best way to prevent clinical mastitis is with an efficient drying program. Additionally it has been shown that a therapy with an aggressive antimicrobial during drying offer better milk production results in the whole herd at next cycle. For getting an excellent drying program, there must be a very long acting antimicrobial. Cloxacillin, benzatine salt, in special vehicle of MASTOSEC-T® offers the clinician a long action that goes beyond labor, avoiding growth and colonization of Staphylococcus aureus and Streptococcus agalactie or St. dysgalactie. Although Gram-negative bacteria are not a problem, during drying period, the presence of dihydrostreptomycin cover the eventual possible infection if drying was not fully achieved, and also because one of common etyologies are Streptococcus sp. Synergic action of the β-lactamic cloxacillin and penicillin G benzatine with that of aminoglicosid dihydrostreptomycin of de MASTOSEC-T® over this bacterial genre.
Design of de MASTOSEC-T® considered that penicillin G is still the most efficient antimicrobial available against genre Streptococcus sp., but because of the appearance of Streptococcus sp., strains resistant to penicillin G, it was considered very useful to include cloxacillin in formulation, because it is resistant to penicillinase or β-lactamase action and remains active against 95% of this bacterial genre with levels as low as 0.5 a 1.0 μg/ml of active ingredient. This is why it is known as the ant-staphylococcus penicillin. Additionally, combination in MASTOSEC-T® offers protection against infections produced by Corynebacterium pyogenes, bacteria from genre Clostridium sp., Haemophilus sp. and Pasteurella sp.
It is important that veterinarian recognize drying importance of the preparation (MASTOSEC-T®) for clinical mastitis, because it effects are not interchangeable.
|
